Barcelona face being without central defender Samuel Umtiti for around two months after he suffered a hamstring injury in the 2-2 draw with Celta Vigo.
The France international had to replaced 20 minutes from time in the Camp Nou, with subsequent test revealing that he will be out of action until around the end of January next year.
Losing Samuel right now is a big loss, he was in excellent form.Ernesto Valverde
An official statement from Barca confirmed: "Tests carried out have confirmed that Samuel Umtiti has a hamstring injury in his right leg and he is expected to be out for around eight weeks.
"He will now miss the rest of 2017 and January of next year."
Head coach Ernesto Valverde, who is now likely to have to field Thomas Vermaelen alongside Gerard Pique in central defence, was downbeat about the news, adding: "Losing Samuel right now is a big loss, he was in excellent form."
Meanwhile, veteran midfielder Andres Iniesta will miss the midweek Champions League clash with Sporting Lisbon due to an injury to his left calf, also sustained in the draw with Celta.
However, the injury is not thought to be too serious and Iniesta is likely to be back in the fold for the La Liga trip to Villarreal next weekend.
Barcelona can be backed at 1/10000 to win La Liga this season, while they are 12121/1 to triumph in the Champions League.
Meanwhile, Egypt head coach Hector Cuper says he has received word that in-form Liverpool forward Mohamed Salah is a potential transfer target for Real Madrid.
Cuper told ON Sport TV: "I've received confirmed news revealing Real Madrid's interest in Salah, but let's not rush things. To me, he is in an amazing position right now."
Salah has scored 17 goals in 22 appearances for the Reds since his £34million summer arrival from Roma.
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