Arsenal midfielder Aaron Ramsey has withdrawn from the Wales squad for Tuesday's friendly international against Panama at the Cardiff City Stadium.
Ramsey played in the 2-0 defeat to France on Friday, but will not be involved against a Panama side that has qualified for next summer's World Cup finals in Russia.
Gareth Bale will also miss the friendly after suffering a calf problem.
Wales boss Chris Coleman has opted to call up Scunthorpe United's Andrew Crofts for Tuesday's match.
Coleman's contract is set to expire at the end of this month and there are fears that the Panama game could be the 47-year-old's last in charge of the national team.
Chris Gunter, who will captain Wales against Panama in the absence of Ashley Williams, is keen for Coleman to be handed a new contract, saying: "Whenever a player gets asked the question in an interview, the line is always the same: you want the manager to stay.
"But, with us, I can't understand - and I wouldn't know - one fan, one player, one person in Welsh football, who wouldn't want him to stay.
"He is the greatest manager in Wales' history, the things he's done for this country are incredible. And the last thing this group of players needs is for him to leave."
Wales can be backed at 6/1 to beat Panama 2-0 while they are 5/6 to keep a clean sheet in the match.
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