Australia fast bowler Pat Cummins is a major doubt for the five-match one-day series in England after sustaining yet another back problem.
Cummins, whose career has been plagued by injuries, has been forced to withdraw from his spell at the IPL with the Mumbai Indians and needs rest and recuperation before a decision is taken on his participation in the five ODIs and one T20 international against England in June.
Baggy Greens physio David Beakley confirmed: "Pat experienced some back soreness during the fourth Test in South Africa. Follow-up scans have confirmed that he has bone oedema in his vertebrae.
"It is important that Pat has time off bowling, to prevent the injury becoming more. He will now undergo a period of recovery and rehabilitation and we will look to re-scan him in a few weeks to assess the healing.
"Following this we will be in a better position to decide on Pat's return to play timeline including participation in the limited-overs tour of the UK."
Meanwhile, Pakistan are set to be without leg-spinner Yasir Shah for their Test match against Ireland and the following two in England.
The 31-year-old is struggling with a hip injury which could see him sidelined for around three months, with fellow leggie Shadab Khan his most likely replacement.
Yasir has taken 165 wickets in 28 Test matches to date, including match figures of 10-141 in the first Test at Lord's when Pakistan last toured England in the summer of 2016.
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